What is detrusor activity?
David Richardson Detrusor overactivity is defined as a urodynamic observation characterized by involuntary detrusor contractions during the filling phase that may be spontaneous or provoked.
What causes detrusor instability?
It is defined as an involuntary phasic detrusor contraction of any pressure associated with symptoms of urge or leakage while the patient is attempting to inhibit micturition. The etiology is unknown but it has been associated with congenital causes, aging, stress incontinence, and bladder outlet obstruction.
How is detrusor instability diagnosed?
Detrusor instability is a urodynamic diagnosis made when the detrusor is shown objectively to contract, spontaneously or on provocation, during the filling phase of a cystometrogram while the patient is attempting to inhibit micturition.
What nerve controls detrusor muscle?
| Detrusor muscle | |
|---|---|
| Nerve | Sympathetic – hypogastric n. (T10-L2) Parasympathetic – pelvic splanchnic nerves (S2-4) |
| Actions | Sympathetic relaxes, to store urine Parasympathetic contracts, to urinate |
| Identifiers | |
| Latin | musculus detrusor vesicae urinariae |
How is detrusor overactivity treated?
Oxybutynin and tolterodine are the more commonly used anticholinergics in OAB treatment. Oxybutynin (Ditropan) was among the first anticholinergic agents to be used to treat detrusor overactivity, and its efficacy in treating OAB is well documented.
Which drugs are useful in detrusor instability?
Which is the most effective anticholinergic?
- Oxybutynin. Oxybutynin is the most widely used anticholinergic for overactive bladder.
- Propantheline. Propantheline is an old drug that is still widely used in Australia.
- Imipramine.
- Tolterodine.
- Trospium.
- Darifenacin.
- Solifenacin.
- Extended-release products.
What is detdetrusor function?
Detrusor Function. Overactive. Synonym: Automatic, hyperreflexic. Level of injury: above the reflex voiding center in the sacral portion of the spinal cord (effectively at T12 or above)
What type of muscle is the detrusor?
Anatomical terms of muscle. The detrusor muscle, also detrusor urinae muscle, muscularis propria of the urinary bladder and (less precise) muscularis propria, is smooth muscle found in the wall of the bladder.
What does underactive detrusor during micturition mean?
An underactive detrusor during micturition implies that the detrusor contraction is of inadequate magnitude or duration to effect bladder emptying within a normal time span. Acontractile detrusor is one that cannot be demonstrated to contract during urodynamic studies.
What is the function of the detrusor muscle of the bladder?
Urinary bladder. [edit on Wikidata] The detrusor muscle, also detrusor urinae muscle, muscularis propria of the urinary bladder and (less precise) muscularis propria, is smooth muscle found in the wall of the bladder. The detrusor muscle remains relaxed to allow the bladder to store urine, and contracts during urination to release urine.